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Growth strategy for legacy immunology portfolio

Repositioning an established immunology business to unlock growth across Europe

The why

The client had an established and profitable portfolio in allergies and immunology, with a dominating position in Europe. However, the business was still operating below its potential. Low awareness, weak patient pathways, and low prescription rates were limiting uptake across markets, while the overall ambition for the portfolio remained underdefined. Leadership needed a clearer view of how much growth could be unlocked and what it would take to realise it.

The challenge

The portfolio lacked a clear, ambition-led therapeutic area aspiration to guide development, prioritisation, and investment. Leadership could see that the business had further potential, but there was no shared view on how far to push it, which growth avenues were genuinely attractive, or which were realistic given the portfolio, market dynamics, and organisational constraints.

At the same time, leadership focus was limited. The business was performing well enough to avoid immediate pressure, but not well enough to realise its full potential without sharper direction. That created a familiar risk for established portfolios: too little strategic attention to make deliberate choices, and too much uncertainty to commit to a more ambitious growth path.

How we helped

Through a collaboration with functions across the organisation, we established and concretized distinct strategic growth paths, to allow leadership to make actual choices and progress the portfolio.

Outcome

The strategy showcased a revenue upside of >100% revenue growth in 2030, at 70+% profit margin

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What moved the needle

Cross-functional collaboration that tested feasibility early The work was shaped through close collaboration with a cross-functional client working group, bringing together perspectives from commercial, CMC, clinical, manufacturing, regulatory, finance, and other key functions. That made it possible to identify barriers early, test assumptions across the full value chain, and ensure that proposed growth paths were not only attractive on paper but feasible in practice.
Concrete options that allow for choice The strategic options were developed as clear and actionable growth paths rather than high-level directions. Each one was fleshed out with concrete initiatives, organisational implications, required investments, delivery considerations, and risk profiles. That gave leadership a stronger basis for comparison and made the strategic choice easier to navigate and to commit to.
Partner

Jonas T. Karlsen, Ph.D.

Jonas is a life science strategist supporting executives drive progress across the value chain. He is an expert in bridging strategy and execution via global operating model design and transformation rooted in strategic objectives. He engages with structured top-down thinking and a pragmatic and collaborative approach to mobilise organizations and make things happen.

Jonas holds a Ph.D. in biophysics from the Technical University of Denmark, DTU, and further studied at California Institute of Technology. Recipient of the Ministry of Sciences Elite Research Award.

Selected experience

  • Ecosystem integration and external innovation pipeline
  • Lab of the future capability building and operating model design
  • Global clinical operating model design and transformation
  • Pre-launch strategy for cardiometabolic TA development

 

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